The Shakori were associated with other Siouan tribes of the Piedmont, such as the Sissipahaw and Eno, and they all are believed to have spoken the same Siouan language. Scholars debate whether the Shakori, Eno, and Sissipahaw were different tribes or bands of the same tribe. This distinction became moot as the tribes merged with one another as their numbers decreased. Although they merged into remnants of other tribes and the larger Catawba, their Siouan dialect survived as late as 1743 among the Eno. They resisted Catawba assimilation the longest.
Although their origins are uncertain, the Shakori were among the Siouan-speaking tribes found in the Piedmont area of numerous southern states. They are believed to have joined against the English colonists in the Yamasee War. It is likely that by this time they were already confederated or merged with remnants of other tribes, such as the Saponi. Descendants with partial Shakori ancestry are likely among the Catawba and other regional groups, but the Shakori are extinct as a tribe.*